| Customization: | Available |
|---|---|
| Appearance: | White Powder |
| Package: | Zip Bag and Alumium Bag |
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Pimavanserin is the active pharmaceutical ingredient of Nuplazid®, which was approved by the FDA in 2016 for the treatment of hallucinations and delusions associated with psychosis in patients suffering from Parkinson's disease. Its exact mechanism of action is unclear. The drug exhibits a combination of inverse agonist and antagonist activity at the serotonin 2A receptors (5-HT2A) and, to a lesser extent, at the 5-HT2C receptors in the central nervous system, which is believed to contribute to its antipsychotic activity. Pimavanserin is absorbed in the gastrointestinal tract and is highly bound to plasma protein (approximately 95%). Following the administration of a single 34-mg dose of pimavanserin, the time to maximum plasma concentration is six hours, the half-life is approximately 57 h and the mean (standard deviation, SD) apparent volume of distribution is 2,173 (307) L. Pimavanserin is metabolized in the liver predominantly by cytochrome P450 (CYP3A4 and CYP3A5) and does not cause significant CYP3A4 inhibition or induction. It has a major active N-desmethylated metabolite AC-279, whose half-life is 200 h.
Recommended Dosage NUPLAZID (pimavanserin) is available as:
Typical Properties:
Atypical antipsychotics FDA Approved 2016
Antidepressant Drug
Treatment of hallucinations and delusions associated with Parkinson's disease psychosis
| Product name | Pimavanserin Tartrate |
| CAS No. | 706782-28-7 |
| Molecular formula | C54H74F2N6O10 |
| Molecular weight | 1005.1963664 |
| Purity | 99% |
| Appearance | White or almost white powder |
| Package | Aluminum Bag;Drums |
| Shelf life | 2 years |
| By Express | By Air | By Sea |
| Suitable for under 50kg | Suitable for more than 50kg | Suitable for more than 500kg |
| Fast: 3-7 days | Fast: 3-7 days | Slow: 3-10 days |
| High cost | Medium cost | Low cost |
| Door to door service | Port to port service | Port to port service |
Customized Package Is Available.
We will always do our best to utilize the quickest and most affordable way for customers to receive orders.
And follow up with customers via email for all shipment details as well as updated track information until it arrives without damage.
Shanghai HuiRui Chemical Technology Co., Ltd.(HuiCHem) is a high-tech enterprise engaged in the area of health care & nutrition. HuiChem have been working closely with our customers we deliver products and solutions that create value and competitive advantage while positively impacting the world we live in, as well as attentive service for the purpose to meet the demand of customers, spare no effort to create value for customers.
HuiChem is now headquartered in Shanghai, and has offices in Jiangsu, Shandong, Anhui and HongKong. Its Shanghai headquarters has nearly 2000 square meters of operation premises, including a total of over 1500 square meters of synthesis laboratories and more than 200 square meters of analysis laboratories (equipped with AAS, LC-MS, FTIR, NMR and other basic test equipment). We have set up two pilot scale laboratories, which lay speedy and stable foundation for process amplification and production of superior products. Besides, we have partner factories that are responsible for the commercial production in Jiangsu Province and Shandong Province. All of those, ensuring growing customer demand and smooth commercial production. We have been certified ISO9001:2008 and ISO14001:2004. The company has established good cooperative relationships with Shanghai Institute of Organic Chemistry of Chinese Academy of Sciences(SIOC), Shanghai Institute of Materia Medica (SIMM), University of Science and Technology of China and Fudan University, and carried out a variety of creative R&D cooperation activities.
We attach great importance to technical innovation and follow the latest dynamic of discovery and development to research and develop new products relying on advanced technology of synthetic chemistry, medicinal chemistry, biochemistry and analytical chemistry. We also pay attention to introduce and foster professional and technical personnel, the company has a group of vigorous and well-trained employees, and strong technical R&D forces. HuiChem has established a new system covering research and development, production and sales. Based on advanced equipment and strict management, always pursue the "open, inclusion, innovation, sharing" business philosophy, creating a win-win cooperation platform.
Everything originates from innovation. HuiChem combines the power of science and the passion of innovation. We believe to connect chemistry and innovation with the principles of sustainability to create a healthy life.
Service:
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
Advantages:
1. Faster delivery: Sample order in stock and 3-7 days for bulk production.
2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
3. After-Sale Service:
1)International Authorized Third-Party Test For The Products You Demand.
2)60 Days Warranty of quality of goods.
Q1. How does your factory control quality?
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