Customization: | Available |
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Powder: | Yes |
Customized: | Non-Customized |
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What is Ruxolitinib phosphate?
The phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.
Ruxolitinib phosphate is approved to treat:
1) Myelofibrosis (a bone marrow disease) that is intermediate or high-risk
2) Primary myelofibrosis.
3) Post-polycythemia vera myelofibrosis.
4) Post-essential thrombocythemia myelofibrosis.
By Express | By Air | By Sea |
Suitable for under 1kg | Suitable for more than 1kg | Suitable for more than 10kg |
Fast: 3-7 days | Fast: 5-9 days | Slow: 10-30 days |
High cost | Medium cost | Low cost |
Door to door service | Port to port service | Port to port service |
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Q1. How does your factory control quality?
All the raw material purchasing and production quality control are strictly following the ISO9001: 2008 management system. Besides, the full-featured detection equipment and GMP quality management system to provide the strongest guarantee for high quality product. We can provide our customers the detailed test report for the quality evaluation before the sample.